Evidence for Independent Segregation of the VP6-and-NSP4-Encoding Genes in Human Group A Rotavirus G5P[6] Strains


VP6- and NSP4- encoding genes of human group A rotavirus strain LL3354 with rare genotypes (G5P[6]), detected from China Lulong, was characterized by reverse transcription-PCR followed by sequencing and phylogenetic analysis. LL3354 joins the major cluster of SGI rotaviruses in the VP6 phylogenetic tree, However, It was identified as NSP4 genotype B. Our results provide evidence for independent segregation of the VP6- and NSP4-encoding genes in human group A rotaviruses.


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